Séminaire de Ondrej Hovorka (Univ. Southampton) :
Understanding collective phenomena and locomotion of magnetic nanoparticles for nanomedicine
le vendredi 13 septembre 2019 à 11h, salle des conseils de l’UFR de Chimie (32-42.101).
Résumé
Understanding collective phenomena and locomotion of magnetic nanoparticles for nanomedicine
Ondrej Hovorka
Assistant Professor in Computational Modelling, Faculty of Engineering and Physical Sciences, University of Southampton
In this talk we review our research activities related to computational modelling of magnetic nanoparticles in the context of biomedical applications, such as magnetic particle hyperthermia, magnetic resonance imaging or directed particle transport for drug delivery. The emphasis will be given on studying the effects of inter-particle interactions, which can lead to suppressed or enhanced performance in applications depending on the extent of nanoparticle aggregation and clustering. We will also discuss our recent work into using nanoparticles as active swimmers for enhanced transport in complex biological environments.
References :
1. M. Fernández-Medina, X. Qian, O. Hovorka, B. Städler , “Disintegrating polymer multilayers to jump-start colloidal micromotors”, Nanoscale 11, 733 (2019).
2. Ming-Da Yang, Chien-Hsin Ho, S. Ruta, R. Chantrell, K. Krycka, O. Hovorka, Fu-Rong Chen, Ping-Shan Lai, Chih-Huang Lai, “Magnetic Interaction of Multifunctional Core–Shell Nanoparticles for Highly Effective Theranostics”, Advanced Materials, 1802444 (2018).
3. D. Niculaes, A. Lak, G. C. Anyfantis, S. Marras, O. Laslett, S. K. Avugadda, M. Cassani, D. Serantes , O. Hovorka, R. Chantrell, T. Pellegrino, “Asymmetric Assembling of Iron Oxide Nanocubes for Improving Magnetic Hyperthermia Performance”, ACS Nano 11, 12121 (2017).
4. O. Hovorka, “Thermal activation in statistical clusters of magnetic nanoparticles”, Journal of Physics D : Applied Physics 50, 044004 (2017).
5. S. Ruta, R. W. Chantrell, O. Hovorka, “Unified model of hyperthermia via hysteresis heating in systems of interacting magnetic nanoparticles”, Scientific Reports 5, 9090 (2015).
